Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 16891

A sealed prediction that did not hold.

HSD17B3 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 16890, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 16891
    01 Nov 2026, 02:37 UTC

    HSD17B3

    dopamine neurons, braak

    predictionHSD17B3 in dopamine neurons tracks Braak Lewy-body stage

    registered9f9e2a947f723827

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HSD17B3 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    2bce02f200fcf21b817ae6c6…
    follows 4e950104a2b7…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 16891: HSD17B3 in dopamine neurons, braak

cell type
HSD17B3 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HSD17B3 in dopamine neurons.

case closed: nothing better to follow up.