Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 13263

A sealed prediction that did not hold.

HAND2 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 13262, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 13263
    28 Oct 2026, 18:05 UTC

    HAND2

    dopamine neurons, braak

    predictionHAND2 in dopamine neurons tracks Braak Lewy-body stage

    registered2313fa6c35093eea

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HAND2 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    c5db362858da2a1a274647bb…
    follows d2affa07326e…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 13263: HAND2 in dopamine neurons, braak

cell type
HAND2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HAND2 in dopamine neurons.

case closed: nothing better to follow up.