Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 12085

A sealed prediction that did not hold.

HOXD1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 12084, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 12085
    27 Oct 2026, 16:12 UTC

    HOXD1

    dopamine neurons, braak

    predictionHOXD1 in dopamine neurons tracks Braak Lewy-body stage

    registeredde17dca01893f2b2

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HOXD1 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    fc8f4931bca30d235a4ad801…
    follows 907a12baf142…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 12085: HOXD1 in dopamine neurons, braak

cell type
HOXD1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HOXD1 in dopamine neurons.

case closed: nothing better to follow up.