Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

ATXN8

ataxin 8

translation score 0.37, read 2026-10-18; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.38 (overall 0.24)0.38
cell type
Human Protein Atlas
not in the Protein Atlas0.00
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
5 Parkinson's papers of 360.76
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 1782

Sealed predictions

  1. ATXN8 in dopamine neurons, braakn/a → n/areceipt 1789

Swarm cases

receipt 1789: ATXN8 in dopamine neurons, braak

cell type
ATXN8 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for ATXN8 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts