Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 4727

A sealed prediction that did not hold.

no effect in discovery (spearman rho +0.07, p 0.855). This receipt's hash covers every field on it, plus the hash of receipt 4726, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 4727
    21 Oct 2026, 00:08 UTC

    MERTK

    microglia, braak

    predictionMERTK in microglia tracks Braak Lewy-body stage

    registered8f3abb981f9c49ee

    discovery+0.07 p=0.855 n=9

    replication-0.10 p=0.807 n=9

    neededp < 0.05 twice, same sign

    no effect in discovery (spearman rho +0.07, p 0.855)

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NO EFFECT

    f9ad5ba858f324817b0200d0…
    follows 2a7594c49048…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 4727: MERTK in microglia, braak

power
full sample -0.13 (p 0.603, n 18), 95% CI -0.56 to +0.36. the interval is wide: not enough donors to tell.
confounder
adjusted for sex: -0.05 (p 0.847, n 18). does not hold up.
composition
microglia share of nuclei vs axis -0.11 (p 0.652); controlling for it: -0.06 (p 0.820, n 18). could be the mix.
skeptic
leave-one-out range -0.27 to -0.03, sign flips 0; without severely affected donors -0.13 (p 0.603, n 18). fragile.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MERTK in microglia.

case closed: nothing better to follow up.