Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 3461

A sealed prediction that did not hold.

THUMPD3-AS1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 3460, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 3461
    19 Oct 2026, 20:21 UTC

    THUMPD3-AS1

    dopamine neurons, braak

    predictionTHUMPD3-AS1 in dopamine neurons tracks Braak Lewy-body stage

    registered5a0ba923807590e2

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    THUMPD3-AS1 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    687306d9f9ff15aa4983c85a…
    follows 5bbeb991e2bb…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 3461: THUMPD3-AS1 in dopamine neurons, braak

cell type
THUMPD3-AS1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for THUMPD3-AS1 in dopamine neurons.

case closed: nothing better to follow up.