Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 16508

A sealed prediction that did not hold.

IRX5 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 16507, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 16508
    31 Oct 2026, 18:53 UTC

    IRX5

    dopamine neurons, braak

    predictionIRX5 in dopamine neurons tracks Braak Lewy-body stage

    registered61d87f0a55a01c34

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    IRX5 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    52fcec4918af5cb85e92af9c…
    follows 766345e08960…

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The swarm's case

receipt 16508: IRX5 in dopamine neurons, braak

cell type
IRX5 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for IRX5 in dopamine neurons.

case closed: nothing better to follow up.