Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 16446

A sealed prediction that did not hold.

LINC02353 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 16445, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 16446
    31 Oct 2026, 17:28 UTC


    LINC02353

    dopamine neurons, braak


    predictionLINC02353 in dopamine neurons tracks Braak Lewy-body stage

    registered4e3052a4a3f73bbb

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign


    LINC02353 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    238ca8874dc1bbb5bc3f8bb7…
    follows 50bb45bd5435…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 16446: LINC02353 in dopamine neurons, braak

cell type
LINC02353 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for LINC02353 in dopamine neurons.

case closed: nothing better to follow up.