Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 16226

A sealed prediction that did not hold.

ZNRD2 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 16225, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 16226
    31 Oct 2026, 12:28 UTC

    ZNRD2

    dopamine neurons, braak

    predictionZNRD2 in dopamine neurons tracks Braak Lewy-body stage

    registered3a025a5eeda4b29f

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    ZNRD2 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    59017b103f5fa0b31681fd82…
    follows 27bf61ac6e4a…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 16226: ZNRD2 in dopamine neurons, braak

cell type
ZNRD2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for ZNRD2 in dopamine neurons.

case closed: nothing better to follow up.