Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 15503

A sealed prediction that did not hold.

CLDN3 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 15502, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 15503
    30 Oct 2026, 21:08 UTC

    CLDN3

    dopamine neurons, braak

    predictionCLDN3 in dopamine neurons tracks Braak Lewy-body stage

    registerede05d593bb2dc722e

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    CLDN3 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    7fc1409737ff21b74eae2113…
    follows 41dd9a3df103…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 15503: CLDN3 in dopamine neurons, braak

cell type
CLDN3 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CLDN3 in dopamine neurons.

case closed: nothing better to follow up.