Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 14875

A sealed prediction that did not hold.

HOXB8 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 14874, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 14875
    30 Oct 2026, 05:45 UTC

    HOXB8

    dopamine neurons, braak

    predictionHOXB8 in dopamine neurons tracks Braak Lewy-body stage

    registered4949629099df2d75

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HOXB8 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    cfe6960f105b3d8e0e660d0b…
    follows 0cee57c5503d…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 14875: HOXB8 in dopamine neurons, braak

cell type
HOXB8 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HOXB8 in dopamine neurons.

case closed: nothing better to follow up.