Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 14075

A sealed prediction that did not hold.

CRNDE is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 14074, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 14075
    29 Oct 2026, 12:18 UTC

    CRNDE

    dopamine neurons, braak

    predictionCRNDE in dopamine neurons tracks Braak Lewy-body stage

    registeredefc20d386c291911

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    CRNDE is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    f462bfc4a8d5dd9ad7e4b853…
    follows 2cff85d1d645…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 14075: CRNDE in dopamine neurons, braak

cell type
CRNDE is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CRNDE in dopamine neurons.

case closed: nothing better to follow up.