Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 12291

A sealed prediction that did not hold.

TPSG1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 12290, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 12291
    27 Oct 2026, 20:54 UTC


    TPSG1

    dopamine neurons, braak


    predictionTPSG1 in dopamine neurons tracks Braak Lewy-body stage

    registered139cd1c7a10928e0

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign


    TPSG1 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    7519bd8eff02a9389b10416d…
    follows cd21b6f8a5a3…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 12291: TPSG1 in dopamine neurons, braak

cell type
TPSG1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TPSG1 in dopamine neurons.

case closed: nothing better to follow up.