Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 1015

A sealed prediction that did not hold.

HES4 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 1014, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 1015
    17 Oct 2026, 12:12 UTC

    HES4

    dopamine neurons, braak

    predictionHES4 in dopamine neurons tracks Braak Lewy-body stage

    registeredeb0f1c6487d3dbf9

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HES4 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    a2f4e27209ecd0c46a3faba5…
    follows a98aa01aa970…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 1015: HES4 in dopamine neurons, braak

cell type
HES4 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HES4 in dopamine neurons.

case closed: nothing better to follow up.