Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

WNT1

Wnt family member 1

translation score 0.39, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.07 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (early primary spermatocytes)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
56 Parkinson's papers of 2,9570.47
pathways
Reactome
6 pathways; mostly vesicle traffic1.00

No case: the score is under the bar. Receipt 3948

Sealed predictions

  1. WNT1 in dopamine neurons, braakn/a → n/areceipt 3956

Swarm cases

receipt 3956: WNT1 in dopamine neurons, braak

cell type
WNT1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for WNT1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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