Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

UNCX

UNC homeobox

translation score 0.45, read 2026-10-29; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced in brain excitatory neurons (11 nCPM)1.00
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 13912

Sealed predictions

  1. UNCX in dopamine neurons, braakn/a → n/areceipt 13919

Swarm cases

receipt 13919: UNCX in dopamine neurons, braak

cell type
UNCX is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for UNCX in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts