Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

TPTE

transmembrane phosphatase with tensin homology

translation score 0.49, read 2026-10-18; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.24 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (early primary spermatocytes)0.10
chemistry
Open Targets
reachable by antibody0.36
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
1 pathway; mostly vesicle traffic1.00

No case: the score is under the bar. Receipt 1800

Sealed predictions

  1. TPTE in dopamine neurons, braakn/a → n/areceipt 1806

Swarm cases

receipt 1806: TPTE in dopamine neurons, braak

cell type
TPTE is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TPTE in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts