Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

TLR9

toll like receptor 9

translation score 0.48, read 2026-10-19; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.09 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (tuft cells)0.10
chemistry
Open Targets
compounds already reach it: lefitolimod, hydroxychloroquine sulfate, bazlitoran +81.00
trials
ClinicalTrials.gov
1 Parkinson's trial, 0 stopped1.00
literature
PubMed
21 Parkinson's papers of 7,1780.59
pathways
Reactome
7 pathways; mostly vesicle traffic1.00

No case: the score is under the bar. Receipt 2843

Sealed predictions

  1. TLR9 in dopamine neurons, braakn/a → n/areceipt 2850

Swarm cases

receipt 2850: TLR9 in dopamine neurons, braak

cell type
TLR9 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TLR9 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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