Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

SOX1

SRY-box transcription factor 1

translation score 0.27, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.07 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (bergmann glia)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
20 Parkinson's papers of 6340.60
pathways
Reactome
2 pathways; mostly other0.30

No case: the score is under the bar. Receipt 4146

Sealed predictions

  1. SOX1 in dopamine neurons, braakn/a → n/areceipt 4153

Swarm cases

receipt 4153: SOX1 in dopamine neurons, braak

cell type
SOX1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for SOX1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts