Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

SEPTIN6

septin 6

translation score 0.41, read 2026-10-30; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 220.91
pathways
Reactome
Reactome did not answer (Reactome: HTTP 521)0.00

No case: the score is under the bar. Receipt 14775

Sealed predictions

  1. SEPTIN6 in dopamine neurons, braakn/a → n/areceipt 14781

Swarm cases

receipt 14781: SEPTIN6 in dopamine neurons, braak

cell type
SEPTIN6 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for SEPTIN6 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts