Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

S100G

S100 calcium binding protein G

translation score 0.32, read 2026-10-27; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (retinal ganglion cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 12182

Sealed predictions

  1. S100G in dopamine neurons, braakn/a → n/areceipt 12189

Swarm cases

receipt 12189: S100G in dopamine neurons, braak

cell type
S100G is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for S100G in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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