Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

OTUD6A

OTU deubiquitinase 6A

translation score 0.30, read 2026-10-23; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.02 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (early primary spermatocytes)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 280.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 7971

Sealed predictions

  1. OTUD6A in dopamine neurons, braakn/a → n/areceipt 7979

Swarm cases

receipt 7979: OTUD6A in dopamine neurons, braak

cell type
OTUD6A is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for OTUD6A in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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