Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

NTMT2

N-terminal Xaa-Pro-Lys N-methyltransferase 2

translation score 0.41, read 2026-10-21; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.09 (overall 0.05)0.09
cell type
Human Protein Atlas
cell type enhanced outside the brain (cardiomyocytes)0.10
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 4965

Sealed predictions

  1. NTMT2 in dopamine neurons, braakn/a → n/areceipt 4972

Swarm cases

receipt 4972: NTMT2 in dopamine neurons, braak

cell type
NTMT2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for NTMT2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts