Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

NPFF

neuropeptide FF-amide peptide precursor

translation score 0.39, read 2026-10-27; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (epididymal principal cells)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 4050.91
pathways
Reactome
2 pathways; mostly other0.30

No case: the score is under the bar. Receipt 12059

Sealed predictions

  1. NPFF in dopamine neurons, braakn/a → n/areceipt 12068

Swarm cases

receipt 12068: NPFF in dopamine neurons, braak

cell type
NPFF is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for NPFF in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts