Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

NOG

noggin

translation score 0.43, read 2026-10-27; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
group enriched outside the brain (retinal pigment epithelial cells)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 1,1690.91
pathways
Reactome
2 pathways; mostly growth signalling0.60

No case: the score is under the bar. Receipt 11841

Sealed predictions

  1. NOG in dopamine neurons, braakn/a → n/areceipt 11848

Swarm cases

receipt 11848: NOG in dopamine neurons, braak

cell type
NOG is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for NOG in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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