Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

MRGPRD

MAS related GPR family member D

translation score 0.41, read 2026-10-30; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
not detected in single-cell data0.00
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 15591

Sealed predictions

  1. MRGPRD in dopamine neurons, braakn/a → n/areceipt 15598

Swarm cases

receipt 15598: MRGPRD in dopamine neurons, braak

cell type
MRGPRD is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MRGPRD in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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