Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

MIF

macrophage migration inhibitory factor

translation score 0.48, read 2026-10-19; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.09 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
compounds already reach it: iguratimod, imalumab0.90
trials
ClinicalTrials.gov
11 Parkinson's trials, 0 stopped1.00
literature
PubMed
60 Parkinson's papers of 7,8330.46
pathways
Reactome
3 pathways; mostly immune signalling0.90

No case: the score is under the bar. Receipt 2969

Sealed predictions

  1. MIF in dopamine neurons, braakn/a → n/areceipt 2976

Swarm cases

receipt 2976: MIF in dopamine neurons, braak

cell type
MIF is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MIF in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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