Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

MBLAC1

metallo-beta-lactamase domain containing 1

translation score 0.32, read 2026-10-26; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
4 Parkinson's papers of 120.79
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 10552

Sealed predictions

  1. MBLAC1 in dopamine neurons, braakn/a → n/areceipt 10559

Swarm cases

receipt 10559: MBLAC1 in dopamine neurons, braak

cell type
MBLAC1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MBLAC1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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