Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

LYNX1-SLURP2

LYNX1-SLURP2 readthrough

translation score 0.32, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.06 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (esophageal apical cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
Reactome did not answer (Reactome: The operation was aborted due to timeout)0.00

No case: the score is under the bar. Receipt 4309

Sealed predictions

  1. LYNX1-SLURP2 in dopamine neurons, braakn/a → n/areceipt 4317

Swarm cases

receipt 4317: LYNX1-SLURP2 in dopamine neurons, braak

cell type
LYNX1-SLURP2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for LYNX1-SLURP2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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