Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

LCE1A

late cornified envelope 1A

translation score 0.35, read 2026-10-29; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (late spermatids)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 14288

Sealed predictions

  1. LCE1A in dopamine neurons, braakn/a → n/areceipt 14295

Swarm cases

receipt 14295: LCE1A in dopamine neurons, braak

cell type
LCE1A is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for LCE1A in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts