Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

IGKV1-8

immunoglobulin kappa variable 1-8

translation score 0.32, read 2026-11-01; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (plasma cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 16820

Sealed predictions

  1. IGKV1-8 in dopamine neurons, braakn/a → n/areceipt 16827

Swarm cases

receipt 16827: IGKV1-8 in dopamine neurons, braak

cell type
IGKV1-8 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for IGKV1-8 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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