Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

H4C13

H4 clustered histone 13

translation score 0.45, read 2026-10-30; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
group enriched outside the brain (erythrocyte progenitors)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
61 pathways; mostly dopamine synapse1.00

No case: the score is under the bar. Receipt 14857

Sealed predictions

  1. H4C13 in dopamine neurons, braakn/a → n/areceipt 14864

Swarm cases

receipt 14864: H4C13 in dopamine neurons, braak

cell type
H4C13 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for H4C13 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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