Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

GSTM1

glutathione S-transferase mu 1

translation score 0.40, read 2026-10-18; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.11 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (urothelial cells)0.10
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
34 Parkinson's papers of 4,5170.53
pathways
Reactome
3 pathways; mostly iron and oxidative stress0.80

No case: the score is under the bar. Receipt 2438

Sealed predictions

  1. GSTM1 in dopamine neurons, braakn/a → n/areceipt 2445

Swarm cases

receipt 2445: GSTM1 in dopamine neurons, braak

cell type
GSTM1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for GSTM1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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