Six readers
| reader | found | score |
|---|---|---|
| genetics Open Targets | no genetic evidence; overall 0.31 from other evidence | 0.00 |
| cell type Human Protein Atlas | cell type enhanced, including microglia; strongest in platelets | 0.75 |
| chemistry Open Targets | a small-molecule pocket | 0.60 |
| trials ClinicalTrials.gov | no Parkinson's trials on record: an open field | 1.00 |
| literature PubMed | 45 Parkinson's papers of 3,308 | 0.50 |
| pathways Reactome | 4 pathways; mostly iron and oxidative stress | 0.80 |
No case: the score is under the bar. Receipt 1195
Sealed predictions
- GPX1 in microglia, braakn/a → n/areceipt 1202
- GPX1 in dopamine neurons, braakn/a → n/areceipt 1203
Swarm cases
receipt 1203: GPX1 in dopamine neurons, braak
- cell type
- GPX1 is not measured in dopamine neurons; looking elsewhere.
- cell type
- no other cell group does better.
- axis
- no measure beats "tracks Braak Lewy-body stage" for GPX1 in dopamine neurons.
case closed: nothing better to follow up.
receipt 1202: GPX1 in microglia, braak
- cell type
- GPX1 is not measured in microglia; looking elsewhere.
- cell type
- no other cell group does better.
- axis
- no measure beats "tracks Braak Lewy-body stage" for GPX1 in microglia.
case closed: nothing better to follow up.
Receipts
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