Six readers
| reader | found | score |
|---|---|---|
| genetics Open Targets | no genetic evidence; overall 0.05 from other evidence | 0.00 |
| cell type Human Protein Atlas | enriched in the midbrain (6 nTPM), where the nigral dopamine neurons sit | 0.90 |
| chemistry Open Targets | hard to drug | 0.00 |
| trials ClinicalTrials.gov | no Parkinson's trials on record: an open field | 1.00 |
| literature PubMed | 75 Parkinson's papers of 1,543 | 0.43 |
| pathways Reactome | 8 pathways; mostly other | 0.30 |
No case: the score is under the bar. Receipt 5017
Sealed predictions
- FOXA2 in dopamine neurons, braakn/a → n/areceipt 5023
In the sealed studies
Swarm cases
receipt 5023: FOXA2 in dopamine neurons, braak
- cell type
- FOXA2 is not measured in dopamine neurons; looking elsewhere.
- cell type
- no other cell group does better.
- axis
- no measure beats "tracks Braak Lewy-body stage" for FOXA2 in dopamine neurons.
case closed: nothing better to follow up.
Receipts
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