Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

FCGR2C

Fc gamma receptor IIc (gene/pseudogene)

translation score 0.41, read 2026-10-20; 2 sealed predictions, 0 held; 3 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.07 from other evidence0.00
cell type
Human Protein Atlas
group enriched, including microglia; strongest in macrophages0.75
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 3928

Sealed predictions

  1. FCGR2C in microglia, braakn/a → n/areceipt 3936
  2. FCGR2C in dopamine neurons, braakn/a → n/areceipt 3937

Swarm cases

receipt 3937: FCGR2C in dopamine neurons, braak

cell type
FCGR2C is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for FCGR2C in dopamine neurons.

case closed: nothing better to follow up.

receipt 3936: FCGR2C in microglia, braak

cell type
FCGR2C is not measured in microglia; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for FCGR2C in microglia.

case closed: nothing better to follow up.

Receipts

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