Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

ENTREP2

endosomal transmembrane epsin interactor 2

translation score 0.47, read 2026-10-23; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.04 (overall 0.02)0.04
cell type
Human Protein Atlas
cell type enhanced, including brain excitatory neurons; strongest in choroid plexus epithelial cells0.75
chemistry
Open Targets
reachable by antibody0.36
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 7430

Sealed predictions

  1. ENTREP2 in dopamine neurons, braakn/a → n/areceipt 7437

Swarm cases

receipt 7437: ENTREP2 in dopamine neurons, braak

cell type
ENTREP2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for ENTREP2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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