Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

DYNLT5

dynein light chain Tctex-type family member 5

translation score 0.41, read 2026-10-23; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.04 (overall 0.02)0.04
cell type
Human Protein Atlas
cell type enhanced outside the brain (ependymal cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
1 pathway; mostly growth signalling0.60

No case: the score is under the bar. Receipt 7200

Sealed predictions

  1. DYNLT5 in dopamine neurons, braakn/a → n/areceipt 7208

Swarm cases

receipt 7208: DYNLT5 in dopamine neurons, braak

cell type
DYNLT5 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for DYNLT5 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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