Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

DLX2

distal-less homeobox 2

translation score 0.39, read 2026-10-17; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.37 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced, including other brain neurons; strongest in tuft cells0.75
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 4560.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 0777

Sealed predictions

  1. DLX2 in dopamine neurons, braakn/a → n/areceipt 0785

Swarm cases

receipt 0785: DLX2 in dopamine neurons, braak

cell type
DLX2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for DLX2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts