Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

DIABLO

diablo IAP-binding mitochondrial protein

translation score 0.52, read 2026-10-30; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.00 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced in other brain neurons (23 nCPM)1.00
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
8 Parkinson's papers of 1,1670.71
pathways
Reactome
5 pathways; mostly mitochondrial quality control1.00

No case: the score is under the bar. Receipt 15603

Sealed predictions

  1. DIABLO in dopamine neurons, braakn/a → n/areceipt 15611

Swarm cases

receipt 15611: DIABLO in dopamine neurons, braak

cell type
DIABLO is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for DIABLO in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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