Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

CSF2

colony stimulating factor 2

translation score 0.49, read 2026-10-21; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.05 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (innate lymphoid cells)0.10
chemistry
Open Targets
compounds already reach it: namilumab, gimsilumab, otilimab +30.81
trials
ClinicalTrials.gov
9 Parkinson's trials, 1 stopped0.91
literature
PubMed
2 Parkinson's papers of 7770.85
pathways
Reactome
5 pathways; mostly immune signalling0.90

No case: the score is under the bar. Receipt 5426

Sealed predictions

  1. CSF2 in dopamine neurons, braakn/a → n/areceipt 5432

Swarm cases

receipt 5432: CSF2 in dopamine neurons, braak

cell type
CSF2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CSF2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts