Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

CDK5R2

cyclin dependent kinase 5 regulatory subunit 2

translation score 0.49, read 2026-10-17; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.30 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced, including other brain neurons; strongest in pancreatic islet cells0.75
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 210.91
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 1301

Sealed predictions

  1. CDK5R2 in dopamine neurons, braakn/a → n/areceipt 1309

Swarm cases

receipt 1309: CDK5R2 in dopamine neurons, braak

cell type
CDK5R2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CDK5R2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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