Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

APOC4

apolipoprotein C4

translation score 0.44, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.12 (overall 0.07)0.12
cell type
Human Protein Atlas
cell type enriched outside the brain (hepatocytes)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
3 pathways; mostly other0.30

No case: the score is under the bar. Receipt 3851

Sealed predictions

  1. APOC4 in dopamine neurons, braakn/a → n/areceipt 3858

Swarm cases

receipt 3858: APOC4 in dopamine neurons, braak

cell type
APOC4 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for APOC4 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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