Six readers
| reader | found | score |
|---|---|---|
| genetics Open Targets | no genetic evidence; overall 0.37 from other evidence | 0.00 |
| cell type Human Protein Atlas | expressed broadly, no clear home in brain cells | 0.40 |
| chemistry Open Targets | compounds already reach it: fadolmidine, guanfacine, ephedrine sulfate +54 | 1.00 |
| trials ClinicalTrials.gov | 2 Parkinson's trials, 1 stopped | 0.60 |
| literature PubMed | 2 Parkinson's papers of 393 | 0.85 |
| pathways Reactome | 6 pathways; mostly energy | 0.60 |
No case: the score is under the bar. Receipt 0820
Sealed predictions
- ADRA2A in dopamine neurons, braakn/a → n/areceipt 0828
Swarm cases
receipt 0828: ADRA2A in dopamine neurons, braak
- cell type
- ADRA2A is not measured in dopamine neurons; looking elsewhere.
- cell type
- no other cell group does better.
- axis
- no measure beats "tracks Braak Lewy-body stage" for ADRA2A in dopamine neurons.
case closed: nothing better to follow up.
Receipts
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